Bishop Malesic was born in Harrisburg, PA in 1960. He graduated from Central Dauphin East High School in Harrisburg in 1978, and studied Biology at Lebanon Valley College in Annville, PA (1978-1981).
After entering the Seminary, he received a BA in Philosophy and a Master of Divinity from the Pontifical Josephinum College in Columbus, OH, and was ordained a priest in 1987 for the Diocese of Harrisburg. He holds a licentiate in canon law from the Catholic University of America, Washington D.C.
Bishop Malesic then served in a number of pastoral roles in the diocese of Harrisburg, including Parochial Vicar at Saint Theresa of the Infant Jesus Parish in New Cumberland (1987-1989) and Saint Rose of Lima Parish in York (1989-1992); chaplain of the York College of Pennsylvania (1989-1992), Millersville University (1992-1996) and Franklin & Marshall College in Lancaster (1993-1996); Adjunct Judicial Vicar (1991-2006), Auditor (1996-1998), Defender of the Bond and Canonical Consultor (1998-2000), and Judicial Vicar (2006-2015) of the Ecclesiastical Tribunal of Harrisburg, and Pastor of Holy Infant Parish in York Haven (2004-2015).
Pope Francis nominated Bishop Malesic as the Bishop of Greensburg on 24 April 2015, and he received episcopal ordination in July of the same year.
Bishop Malesic serves as a member of the Committee on Canonical Affairs and Church Governance and the Subcommittee on the Church in Central and Eastern Europe in the United States Conference of Catholic Bishops.